The human TRPA1 gene encodes the pore-forming subunit of TRPA1, a non-selective cation channel expressed in sensory neurons and hair cells. TRPA1 channels are therapeutic targets in treatment of pain.
|Product Description||Human TRPA1 ion channel-expressing, division-arrested cells.|
|Target Type||Ion Channel|
|Product Type||EZCells™ TT|
|Class||Transient Receptor Potential (TRP)|
|Therapeutic Area||pain & inflammation, pulmonary-respiratory|
|Genbank Accession Number||NM_007332.2.|
|Validated Assay/Platform||FlexStation III|
|References||Doerner JF, Gisselmann G, Hatt H, Wetzel CH.
Transient receptor potential channel A1 is directly gated by calcium ions.
J Biol Chem. 2007 282:13180-13189.
|Mycoplasma Status||Negative (MycoAlert Kit)|
|Growth media||Ham's F12, 10% FBS and induced with 1 µg/mL tetracycline for 24 hour.|
|Growth characteristics||cells remain viable 1–2 days post-thaw|
|Storage and Packaging|
|Packaging||Cryopreserved irradiated cells, 6x106 cells|
|Storage Recommendation||liquid nitrogen|
|Quantity||6 million cells|