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Background
The human GABRA2, GABR2 and GABRG2 genes encode the Cl--selective, ionotropic GABAA receptor-channel. GABAA receptors expressed in neurons are therapeutic targets in treatment of neurological and psychological disorders.
| General Info | |
| Product Description | Human GABAA (α2/β2/γ2) ion channel-expressing, division-arrested cells. |
|---|---|
| Target Type | Ion Channel |
| Product Type | EZCells™ TT |
| Family | Ligand-Gated |
| Receptor | GABA |
| Sub-Type | GABAA (a2β2γ2) |
| Class | Ligand-gated channel |
| Therapeutic Area | psychiatric disorder, seizure-convulsion |
| Gene Name | GABRA2/GABR2/GABRG2 |
| Genbank Accession Number | a2: NM_000807.2; β2: NM_021911; γ2: NM_198904.1 |
| Validated Assay/Platform | FlexStation III |
| EZCell Info | |
| Host cell | CHO-K1 |
| Mycoplasma Status | Negative (MycoAlert Kit) |
| Growth media | Ham's F12; 10% FBS and 1xPen-Strep. |
| Growth characteristics | cells remain viable 1–2 days post-thaw |
| Storage and Packaging | |
| Packaging | Cryopreserved irradiated cells, 6 million cells per vial. |
| Storage Recommendation | liquid nitrogen |
| Quantity | 6 million cells |
