Human ClC-2 Chloride Channel Cell Line

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  • Representative current traces (upper panel) recorded in the vehicle (control) and after equilibration in 3 mM Cd2+. Currents were activated by a hyperpolarizing test pulse to -120 mV, holding potential 0 mV (lower panel). Recording instrument: PatchXpress®.
  • Current amplitude histogram data pooled from 8 independent experiments. Mean amplitude ± SD (at -120 mV) = -3.48 ± 2.09 nA (N = 137 cells). Recording instrument: PatchXpress®.

Human ClC-2 Chloride Channel Cell Line

  • Cat.#:
  • CT6176

Availability: In stock

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Quick Overview

Human ClC-2 chloride ion channel-expressing, stable replicating cell line.

Background

The human CLCN2 gene encodes the pore-forming subunit of a voltage-gated chloride channel expressed in intestinal epithelia and the central nervous system.
General Info
Product Description Human ClC-2 chloride ion channel-expressing, stable replicating cell line.
Target Type Ion Channel
Product Type Replicating Cell Line
Family Chloride
Sub-Type ClC-2
Class Chloride Channel
Therapeutic Area metabolic & gastrointestinal
Related Services Large-scale Cryopreservation
Gene Name CLCN2
Validated Assay/Platform PatchXpress®
References Alexander, S.P.H., Mathie, A. and Peters, J.A. (2007). Guide to Receptors and Channels (GRAC), 2nd edition. Br. J. Pharmacol. 150 (Suppl. 1), S1 – S168.
Host cell CHO-K1
Mycoplasma Status Negative (MycoAlert Kit)
Storage & Packaging
Packaging Cryopreserved cells, 6x106 cells
Storage Recommendation liquid nitrogen
Quantity 6 million cells
Product Documentation
Specification Sheet  Download PDF Document