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Background
The human CFTR gene encodes the pore-forming subunit of the cAMP-regulated epithelial chloride channel associated with cystic fibrosis.
| General Info | |
| Product Description | Human CFTR chloride ion channel-expressing, stable replicating cell line. |
|---|---|
| Target Type | Ion Channel |
| Product Type | Replicating Cell Line |
| Family | Chloride |
| Sub-Type | CFTR |
| Class | Chloride Channel |
| Therapeutic Area | metabolic & gastrointestinal, pulmonary-respiratory |
| Related Services | Large-scale Cryopreservation |
| Gene Name | CFTR |
| Validated Assay/Platform | IonWorks Quattro™, QPatch HT |
| References | Ma, T., Thiagarajah, J. R., Yang, H., Sonawane, N. D., Folli, C., Galietta, L. J., and Verkman, A. S. (2002) Thiazolidinone CFTR inhibitor identified by high-throughput screening blocks cholera toxin-induced intestinal fluid secretion. J. Clin. Invest. 11 |
| Host cell | CHO |
| Mycoplasma Status | Negative (MycoAlert Kit) |
| Storage & Packaging | |
| Packaging | Cryopreserved cells, 1-2x106 cells |
| Storage Recommendation | liquid nitrogen |
| Quantity | 1-2 million cells |
| Product Documentation | |
| Specification Sheet |  Download PDF Document |
