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Background
The human KCND3 gene encodes the pore-forming subunit of a voltage-gated K+ channel. KCNIP2 encodes an auxiliary subunit. Cardiac Kv4.3 channels are therapeutic targets in atrial fibrillation.
| General Info | |
| Product Description | Human Kv4.3/KChlP2.2 ion channel-expressing, division-arrested cells. |
|---|---|
| Target Type | Ion Channel |
| Product Type | EZCells™ TT |
| Family | Potassium, Voltage-Gated |
| Sub-Type | Kv4.3/KChlP2.2 |
| Class | Voltage-gated potassium channel |
| Gene Name | KCND3/KCNlP2 |
| Validated Assay/Platform | PatchXpress® |
| References | Gutman GA, et al. 2005. Pharmacol Rev. 57:473-508. International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels. |
| EZCell Info | |
| Host cell | CHO-K1 |
| Mycoplasma Status | Negative (MycoAlert Kit) |
| Growth media | Ham's F12; 10% FBS |
| Growth characteristics | cells remain viable 1–2 days post-thaw |
| Functional expression | median current amplitude = 1.6 nA |
| Storage and Packaging | |
| Packaging | Cryopreserved irradiated cells, 6x106 cells |
| Storage Recommendation | liquid nitrogen |
| Quantity | 6 million cells |
