Human TRPV6 Channel Cell Line

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  • Concentration-Dependent Ruthenium Red Inhibition of hTRPV6 Current in Manual Patch Clamp. Typical inward current traces (A) elicited by voltage ramps (B) in the absence (control) and after application of a ruthenium red, a non-selective blocker, at 3 and 10 μM.

Human TRPV6 Channel Cell Line

  • Cat.#:
  • CT6169

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Quick Overview

Human TRPV6 ion channel-expressing, tetracycline-inducible, stable replicating cell line.

Background

The human TRPV6 gene encodes the pore-forming subunit of TRPV6, a Ca2+-selective cation channel expressed in kidney and intestine epithelia.
General Info
Product Description Human TRPV6 ion channel-expressing, tetracycline-inducible, stable replicating cell line.
Target Type Ion Channel
Product Type Replicating Cell Line
Family TRP
Sub-Type TRPV6
Class Transient Receptor Potential (TRP)
Therapeutic Area cancer
Related Services Large-scale Cryopreservation
Gene Name TRPV6
Validated Assay/Platform manual patch clamp
References Clapham DE, et al. 2005. Pharmacol Rev 57: 427 - 450. International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels
Host cell HEK293
Mycoplasma Status Negative (MycoAlert Kit)
Storage & Packaging
Packaging Cryopreserved cells, 1-2x106 cells
Storage Recommendation liquid nitrogen
Quantity 1-2 million cells