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Background
The human TRPM4 gene encodes the pore-forming subunit of TRPM4 (transient receptor potential channel, subtype M4), a monovalent cation-selective channel.
| General Info | |
| Product Description | Human TRPM4 ion channel-expressing, transiently transfected cells. |
|---|---|
| Target Type | Ion Channel |
| Product Type | EZCells™ TT |
| Family | TRP |
| Sub-Type | TRPM4 |
| Class | Transient Receptor Potential (TRP) |
| Therapeutic Area | pain & inflammation, vascular |
| Gene Name | TRPM4 |
| Validated Assay/Platform | manual patch clamp |
| References | Clapham DE, et al. 2005. International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels. Pharmacol Rev 57: 427 - 450. Nilius B, Vennekens R. 2006. From cardiac cation channels to |
| EZCell Info | |
| Host cell | HEK293 |
| Mycoplasma Status | Negative (MycoAlert Kit) |
| Growth media | DMEM/F12-PS/10% FBS |
| Functional expression | Initial current amplitude (Mean ± SEM) at +100 mV (1 _M [Ca2+]i activation) = 1.62 ± 0.43 nA (n = 11 cells) |
| Storage and Packaging | |
| Packaging | Cryopreserved, 3x105 cells |
| Storage Recommendation | liquid nitrogen |
| Quantity | 3x105 cells |
| Media | |
| Specification Sheet |  Download PDF Document |
