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Background
The human TRPA1 gene encodes the pore-forming subunit of TRPA1, a non-selective cation channel expressed in sensory neurons and hair cells. TRPA1 channels are therapeutic targets in treatment of pain.
| General Info | |
| Product Description | Human TRPA1 ion channel-expressing, division-arrested cells. |
|---|---|
| Target Type | Ion Channel |
| Product Type | EZCells™ TT |
| Family | TRP |
| Sub-Type | TRPA1 |
| Class | Transient Receptor Potential (TRP) |
| Therapeutic Area | pain & inflammation, pulmonary-respiratory |
| Gene Name | TRPA1 |
| Genbank Accession Number | NM_007332.2. |
| Validated Assay/Platform | FlexStation III |
| References | Doerner JF, Gisselmann G, Hatt H, Wetzel CH. Transient receptor potential channel A1 is directly gated by calcium ions. J Biol Chem. 2007 282:13180-13189. PMID: 17353192 |
| EZCell Info | |
| Host cell | CHO |
| Mycoplasma Status | Negative (MycoAlert Kit) |
| Growth media | Ham's F12, 10% FBS and induced with 1 µg/mL tetracycline for 24 hour. |
| Growth characteristics | cells remain viable 1–2 days post-thaw |
| Storage and Packaging | |
| Packaging | Cryopreserved irradiated cells, 6x106 cells |
| Storage Recommendation | liquid nitrogen |
| Quantity | 6 million cells |
