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Background
The human CLCN2 gene encodes the pore-forming subunit of a voltage-gated Cl- channel expressed in epithelia and neurons.
| General Info | |
| Product Description | Human ClC-2 chloride ion channel-expressing, division-arrested cells. |
|---|---|
| Target Type | Ion Channel |
| Product Type | EZCells™ TT |
| Family | Chloride |
| Sub-Type | ClC-2 |
| Class | Chloride Channel |
| Therapeutic Area | metabolic & gastrointestinal |
| Gene Name | CLCN2 |
| Validated Assay/Platform | manual patch clamp, PatchXpress® |
| References | Alexander SPH, Mathie A and Peters JA. 2007. Guide to Receptors and Channels (GRAC), 2nd edition (2007 revision). Br. J. Pharmacol., 150 (Suppl. 1), S101 - S105. |
| EZCell Info | |
| Host cell | CHO-K1 |
| Mycoplasma Status | Negative (MycoAlert Kit) |
| Growth characteristics | Cells remain viable 1-2 days post-thaw |
| Functional expression | Mean current amplitude at -120 mV ± SEM = 4.46 ± 2.98 nA, n = 15 in PatchXpress®. |
| Storage and Packaging | |
| Packaging | Cryopreserved irradiated cells, 6x106 cells |
| Storage Recommendation | liquid nitrogen |
| Quantity | 6 million cells |
