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Background
The CB2 cannabinoid receptor is expressed primarily in cells of the peripheral immune system and is a target for cannabinoids (Munro et al., 1993; Gerard et al., 1991), the psychoactive ingredients of marijuana. Other members of the cannabinoid family of receptors include the CB1 cannabinoid receptor, which is expressed primarily in brain, and GPR55 (Ryberg, 2007). When activated, the CB2 receptor inhibits adenylate cyclase by coupling through Gi.
| General Info | |
| Product Description | Frozen membranes from CHO-K1 cells expressing recombinant human CB2 Cannabinoid receptors. |
|---|---|
| Target Type | GPCR |
| Product Type | membrane |
| Receptor | Cannabinoid |
| Sub-Type | CB2 |
| Therapeutic Area | neurodegeneration & stroke, pain & inflammation |
| Related Services | Membrane Preparation, GPCR Screening |
| Genbank Accession Number | NM_001841 |
| Membrane Info | |
| Host cell | CHO-K1 |
| Bmax | 34 pmol/mg |
| KD | 0.7 pM |
| Recommended Assay Conditions | Refer to product specification sheet for details |
| Storage and Packaging | |
| Packaging | 0.4 mL of membrane suspension in storage buffer (50 mM Tris-HCl pH 7.5, 5 mM MgCl2, 2.5 mM EDTA, 10% sucrose) at a protein concentration of 1.9 mg/mL |
| Storage Recommendation | Storage at -80oC is recommended. Repeated freeze-thawing of this product is not recommended. |
| Quantity | 400 µL/vial |
| Media | |
| Specification Sheet |  Download PDF Document |
