Human V2 Vasopressin Receptor Membranes

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  • Radioligand binding to membranes from cells expressing hV2 receptor. A crude P1 membrane fraction was made from cells expressing the hV2 receptor. Membranes were incubated with the indicated concentrations of [3H]-8AVP alone (red circles) or along with 8 µM unlabeled 8-AVP to measure non-specific binding. After incubation, membranes were filtered over GF/B filters and counted. Data represent the average of duplicate determinations.

Human V2 Vasopressin Receptor Membranes

  • Cat.#:
  • A141
  • Lot #:
  • 673

Availability: In stock

Price: $397.00
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Quick Overview

Frozen membranes from CHO-K1 cells expressing recombinant human V2 Vasopressin receptors.

Background

The pituitary hormone vasopressin (AVP) is a cyclic nonapeptide that acts by binding to a family of vasopressin receptors that includes the V1a, V1b, and V2 receptors. V2 receptors are expressed in kidney where vasopressin exerts its antidiuretic action.
General Info
Product Description Frozen membranes from CHO-K1 cells expressing recombinant human V2 Vasopressin receptors.
Target Type GPCR
Product Type membrane
Receptor Vasopressin
Sub-Type V2
Therapeutic Area genitourinary, vascular
Related Services Membrane Preparation, GPCR Screening
Genbank Accession Number NM_000054.2
Membrane Info
Host cell CHO-K1
Bmax 19 pmol/mg protein
KD 2 nM
Recommended Assay Conditions Refer to product specification sheet for details
Storage and Packaging
Packaging 0.4 mL of membrane suspension at a protein concentration of 5 mg/mL.
Storage Recommendation Storage at -80oC is recommended. Repeated freeze-thawing of this product is not recommended.
Quantity 400 µL/vial
Media
Specification Sheet  Download PDF Document