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Background
The pituitary hormone vasopressin (AVP) is a cyclic nonapeptide that acts by binding to a family of vasopressin receptors that includes the V1a, V1b, and V2 receptors. V2 receptors are expressed in kidney where vasopressin exerts its antidiuretic action.
| General Info | |
| Product Description | Human V2 Vasopressin Receptor-expressing GPCR (G protein-coupled receptor) division-arrested cells. |
|---|---|
| Target Type | GPCR |
| Product Type | EZCells™ DA |
| Receptor | Vasopressin |
| Sub-Type | V2 |
| Therapeutic Area | genitourinary, vascular |
| Related Services | Membrane Preparation, GPCR Screening |
| Genbank Accession Number | NM_000054.2 |
| Validated Assay/Platform | binding, calcium |
| References | Lolait, S.J., O’Carroll, A.M., et al., (1992) Cloning and characterization of a vasopressin V2 receptor and possible link to nephrongenic diabetes insipidus. Nature 357: 336-339. Birnbaumer, M., Seibold, A., et al., (1992) Molecular cloning of th |
| EZCell Info | |
| Host cell | CHO-K1 |
| Mycoplasma Status | Negative (MycoAlert Kit) |
| Growth media | Ham's F12, 10% FBS, 1% NEAA, 0.4 mg/mL G418 |
| Storage and Packaging | |
| Packaging | Cryopreserved irradiated cells, 6 million cells per vial |
| Storage Recommendation | liquid nitrogen |
| Quantity | 6 million cells |
| Media | |
| Specification Sheet |  Download PDF Document |
