Background
Oxytocin receptors are expressed in uterus and in mammary glands where they mediate important functions in partutition such as contraction of the uterine myometrium during labor and milk letdown. In addition, oxytocin receptors are expressed in a variety of other peripheral tissues and in brain where oxytocin mediates a variety of functions.
| General Info | |
| Synonyms | OTR (Mouse) |
|---|---|
| Product Description | Mouse Oxytocin Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. |
| Target Type | GPCR |
| Product Type | Replicating Cell Line |
| Receptor | Oxytocin |
| Sub-Type | OTR |
| Related Services | Membrane Preparation, Large-scale Cryopreservation, GPCR Screening |
| Genbank Accession Number | NM_001081147; no expressed tags |
| Validated Assay/Platform | calcium |
| References | Gould, B.R. and Zingg, H.H. (2003) Mapping oxytocin receptor gene expression in the mouse brain and mammary gland using an oxytocin receptor-LaxZ reporter mouse. Neuroscience 122: 155-167. Kubota, Y., et al. (1996) Structure and expression of |
| Mycoplasma Status | Negative (MycoAlert Kit) |
| Growth media | Ham's F12, 10% FBS, 0.4 mg/mL G418 |
| Storage & Packaging | |
| Packaging | Cryopreserved cells, 6 million cells per vial |
| Storage Recommendation | liquid nitrogen |
| Stability | 8 passages (4 weeks of continuous culture) |
| Quantity | 6 million cells |
| Product Documentation | |
| Specification Sheet |  Download PDF Document |
