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Background
Alpha-1 adrenergic receptors are widely distributed and mediate a variety of functions including smooth muscle contraction, cardiac stimulation, cellular proliferation, apoptosis and activation of hepatic gluconeogenesis and clycogenolysis. Three distinct alpha-1 adrenergic receptors have been identified and are known as alpha-1a, alpha-1b, and alpha-1c receptors.
| General Info | |
| Synonyms | ADRA1A |
|---|---|
| Product Description | Human Alpha 1A Adrenergic Receptor-expressing GPCR (G protein-coupled receptor) division-arrested cells. |
| Target Type | GPCR |
| Product Type | EZCells™ DA |
| Receptor | Adrenergic |
| Sub-Type | Alpha1a |
| Therapeutic Area | cardiac, genitourinary, vascular |
| Related Services | Membrane Preparation, GPCR Screening |
| Genbank Accession Number | AY389505 |
| Validated Assay/Platform | calcium |
| References | Schwinn, D.A. and Price, R.R. (1999) Molecular pharmacology of human alpha 1-adrenergic receptors: Unique features of the alpha-1a subtype. Eur. Urol. 36: 7-10 Schwinn, D.A. et al . (1995) Cloning and pharmacological characterization of human |
| EZCell Info | |
| Host cell | CHO-K1 |
| Mycoplasma Status | Negative (MycoAlert Kit) |
| Growth media | Ham's F12, 10% dFBS, 1% NEAA, 400 µg/mL G418 |
| Storage and Packaging | |
| Packaging | Cryopreserved irradiated cells, 6 million cells per vial |
| Storage Recommendation | liquid nitrogen |
| Quantity | 6 million cells |
| Media | |
| Specification Sheet |  Download PDF Document |
