Human Serotonin 5-HT6 Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Human 5HT2c Serotonin Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Human Adenosine A1 Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Human A1 Adenosine Receptor-expressing GPCR (G protein-coupled receptor) division-arrested cells. Adenosine is a neuromodulator that is widely distributed in the central and peripheral nervous systems. Modulation of adenosine receptors by selective agonists and antagonists has potential for the treatment of various cardiovascular inflammatory and neurological diseases. Learn More

Human Alpha2a Adrenergic Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Human Alpha2a Adrenergic Receptor-expressing GPCR (G protein-coupled receptor) division-arrested cells. Learn More

Human CB1 Cannabinoid Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Rat CB1 Cannabinoid Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Human CB1 Cannabinoid Receptor-expressing GPCR (G protein-coupled receptor) division-arrested cells. Learn More

Rat CB1 Cannabinoid Receptor-expressing GPCR (G protein-coupled receptor) division-arrested cells. The CB1 cannabinoid receptor is expressed primarily in brain and is a target for cannabinoids. When activated, the CB1 receptor inhibits adenylate cyclase through Gi. Learn More

Human Cholecystokinin CCKA Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Human CCKA Cholecystokinin Receptor-expressing GPCR (G protein-coupled receptor) division-arrested cells. Cholecystokinin (CCK) is a neuropeptide which is widely distributed in the mammalian central nervous system. The CCKA receptor has a limited distribution with highest densities in the hypothalamic nuclei, areas of the hippocampus, the septum, dorsal motor vagal nucleus and interpeduncular nucleus of the brain stem. It also occurs in numerous gastro-intestinal tissues. CCKA receptors affect satiety, pancreatitis, gut motility and have growth-promoting effects on some tumors. Learn More

Human Cholecystokinin CCKB Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Human CCKB Cholecystokinin Receptor-expressing GPCR (G protein-coupled receptor) division-arrested cells. Cholecystokinin (CCK) is a neuropeptide which is widely distributed in the mammalian central nervous system. The CCKB receptor is the predominant subtype in the CNS where it is widely distributed, however, it also occurs in abundance in the gastro-intestinal tract. CCKB receptors have been found to be most abundant in the cerebral cortex, cerebellum, basal ganglia, and amygdale. Animal and human studies using CCKB receptor antagonists have suggested that anxiety, panic attacks, analgesia, and satiety may be modulated through the CCKB receptor. Learn More

Human Gastric Inhibitory Polypeptide Receptor GIPR-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Human GIPR Gastric Inhibitory Polypeptide Receptor-expressing GPCR (G protein-coupled receptor) division-arrested cells. Gastric inhibitory polypeptide (GIP) is a 42-amino acid polypeptide synthesized by K-cells of the duodenum and small intestine. GIP’s principle physiological action is to stimulate insulin secretion from pancreatic β-cells in a glucose-dependent manner. Additional effects of GIP have been described, including effects on lipid metabolism, stimulation of glucagons and somatostatin release. GIP exerts its effects by binding to its specific receptor, the GIP receptor which belongs to the VIP/glucagon/secretin family of G protein-coupled receptors and is positively coupled to adenylyl cyclase but not to phospholipase C. Learn More

Human GPR103 Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Human GPR103 Receptor-expressing GPCR (G protein-coupled receptor) division-arrested cells. Learn More

Human GPR119 Stable-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More