Human Serotonin 5HT2B Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Mouse 5HT2b Serotonin Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Human 5HT2B Serotonin Receptor-expressing GPCR (G protein-coupled receptor) division-arrested cells. Learn More

Mouse 5HT2B Serotonin Receptor-expressing GPCR (G protein-coupled receptor) division-arrested cells. Learn More

Human Adenosine A1 Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Human A1 Adenosine Receptor-expressing GPCR (G protein-coupled receptor) division-arrested cells. Adenosine is a neuromodulator that is widely distributed in the central and peripheral nervous systems. Modulation of adenosine receptors by selective agonists and antagonists has potential for the treatment of various cardiovascular inflammatory and neurological diseases. Learn More

Human A3 Adenosine Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Human Alpha-1a Adrenergic Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Human Alpha 1A Adrenergic Receptor-expressing GPCR (G protein-coupled receptor) division-arrested cells. Learn More

Human Alpha2a Adrenergic Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Human Alpha2a Adrenergic Receptor-expressing GPCR (G protein-coupled receptor) division-arrested cells. Learn More

Human ETA Endothelin Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Human ETA Endothelin Receptor-expressing GPCR (G protein-coupled receptor) division-arrested cells. Endothelins are a family of vasoactive peptides including ET-1, ET-2 and ET-3 in human. The EDNRA receptors (ETA) have a much greater affinity for ET-1 over ET-3 and are expressed abundantly in vascular smooth muscles and stromal tissues. The vasoconstrictor and proliferative effects of ET-1 are primarily mediated by the EDNRA receptor. This makes EDNRA a good target for drug development in a number of cardiovascular diseases, including congestive heart failure, hypertension, stroke, kidney failure, and a variety of non-cardiovascular conditions, such as asthma, chronic obstructive pulmonary disease, pain and cancer. Learn More