Human Chemokine CCR2B Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Human Cholecystokinin CCKB Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Human CCKB Cholecystokinin Receptor-expressing GPCR (G protein-coupled receptor) division-arrested cells. Cholecystokinin (CCK) is a neuropeptide which is widely distributed in the mammalian central nervous system. The CCKB receptor is the predominant subtype in the CNS where it is widely distributed, however, it also occurs in abundance in the gastro-intestinal tract. CCKB receptors have been found to be most abundant in the cerebral cortex, cerebellum, basal ganglia, and amygdale. Animal and human studies using CCKB receptor antagonists have suggested that anxiety, panic attacks, analgesia, and satiety may be modulated through the CCKB receptor. Learn More

Human Cholecystokinin CCKA Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Human CCKA Cholecystokinin Receptor-expressing GPCR (G protein-coupled receptor) division-arrested cells. Cholecystokinin (CCK) is a neuropeptide which is widely distributed in the mammalian central nervous system. The CCKA receptor has a limited distribution with highest densities in the hypothalamic nuclei, areas of the hippocampus, the septum, dorsal motor vagal nucleus and interpeduncular nucleus of the brain stem. It also occurs in numerous gastro-intestinal tissues. CCKA receptors affect satiety, pancreatitis, gut motility and have growth-promoting effects on some tumors. Learn More

Human CB2 Cannabinoid Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Rat CB2 Cannabinoid Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Human CB2 Cannabinoid Receptor-expressing GPCR (G protein-coupled receptor) division-arrested cells. Learn More

Rat CB2 Cannabinoid Receptor-expressing GPCR (G protein-coupled receptor) division-arrested cells.The CB2 cannabinoid receptor is expressed primarily in cells of the peripheral immune system and is a target for cannabinoids. When activated, the CB2 receptor inhibits adenylate cyclase by coupling through Gi. Learn More

Human CB1 Cannabinoid Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Rat CB1 Cannabinoid Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Human CB1 Cannabinoid Receptor-expressing GPCR (G protein-coupled receptor) division-arrested cells. Learn More

Rat CB1 Cannabinoid Receptor-expressing GPCR (G protein-coupled receptor) division-arrested cells. The CB1 cannabinoid receptor is expressed primarily in brain and is a target for cannabinoids. When activated, the CB1 receptor inhibits adenylate cyclase through Gi. Learn More

Human BB2 Bombesin Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Human BB2 Bombesin Receptor-expressing GPCR (G protein-coupled receptor) division-arrested cells. BB2 receptors are widely distributed in the CNS as well as in the gastrointestinal tract and reproductive organs. In CNS, Bombesin-like peptides induce satiety and play a role in thermoregulation and induce histamine-independent pruritus. These peptides also act via the BB2 receptor to regulate sleep disorders, depression and involved in the regulation of emotionally motivated learning, memory and food intake. In the gastrointestinal tract, GRPR receptors are involved in smooth muscle contractility, pancreatic secretion and the release of many other gastrointestinal peptides. Learn More

Human Angiotensin AT1-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Human Alpha2c Adrenergic Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Human Alpha2c Adrenergic Receptor-expressing GPCR (G protein-coupled receptor) division-arrested cells. Learn More

Human Alpha2B Adrenergic Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More