Human GPR40 Free Fatty Acid Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Human GPR40 Receptor-expressing GPCR (G protein-coupled receptor) division-arrested cells. Learn More

Human GPR120 Free Fatty Acid Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Human GPR119 Stable-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Human GPR119 Receptor-expressing GPCR (G protein-coupled receptor) division-arrested cells. Learn More

Human GPR103 Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Human GPR103 Receptor-expressing GPCR (G protein-coupled receptor) division-arrested cells. Learn More

Human Gastric Inhibitory Polypeptide Receptor GIPR-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Human GIPR Gastric Inhibitory Polypeptide Receptor-expressing GPCR (G protein-coupled receptor) division-arrested cells. Gastric inhibitory polypeptide (GIP) is a 42-amino acid polypeptide synthesized by K-cells of the duodenum and small intestine. GIP’s principle physiological action is to stimulate insulin secretion from pancreatic β-cells in a glucose-dependent manner. Additional effects of GIP have been described, including effects on lipid metabolism, stimulation of glucagons and somatostatin release. GIP exerts its effects by binding to its specific receptor, the GIP receptor which belongs to the VIP/glucagon/secretin family of G protein-coupled receptors and is positively coupled to adenylyl cyclase but not to phospholipase C. Learn More

Human Ga16-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Human FPRL1-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Human FPRL1 Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Human FPRL1 Receptor-expressing GPCR (G protein-coupled receptor) division-arrested cells. Learn More

Human ETB Endothelin Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Human ETB Endothelin Receptor-expressing GPCR (G protein-coupled receptor) division-arrested cells. Endothelins are a family of vasoactive peptides that includes ET-1, ET-2 and ET-3. The EDNRA receptors have a much greater affinity for ET-1 over ET-3 and are expressed abundantly in vascular smooth muscles and stromal tissues. The EDNRB receptors bind ET-1, ET-2 and ET-3 with nearly equal affinity and are expressed abundantly in endothelial cells and epithelial tissues. Although the vasoconstrictor and proliferative effects of ET-1 are primarily mediated by EDNRA receptors, EDNRB receptors can also mediate the vasoconstrictor response through ET-1-induced nitric oxide release from endothelial cells. Learn More

Human ETA Endothelin Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Human ETA Endothelin Receptor-expressing GPCR (G protein-coupled receptor) division-arrested cells. Endothelins are a family of vasoactive peptides including ET-1, ET-2 and ET-3 in human. The EDNRA receptors (ETA) have a much greater affinity for ET-1 over ET-3 and are expressed abundantly in vascular smooth muscles and stromal tissues. The vasoconstrictor and proliferative effects of ET-1 are primarily mediated by the EDNRA receptor. This makes EDNRA a good target for drug development in a number of cardiovascular diseases, including congestive heart failure, hypertension, stroke, kidney failure, and a variety of non-cardiovascular conditions, such as asthma, chronic obstructive pulmonary disease, pain and cancer. Learn More

Human Edg-1 (S1P1) Lysophospholipid Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Human Delta Opioid Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More