Human BB2 Bombesin Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Human BB2 Bombesin Receptor-expressing GPCR (G protein-coupled receptor) division-arrested cells. BB2 receptors are widely distributed in the CNS as well as in the gastrointestinal tract and reproductive organs. In CNS, Bombesin-like peptides induce satiety and play a role in thermoregulation and induce histamine-independent pruritus. These peptides also act via the BB2 receptor to regulate sleep disorders, depression and involved in the regulation of emotionally motivated learning, memory and food intake. In the gastrointestinal tract, GRPR receptors are involved in smooth muscle contractility, pancreatic secretion and the release of many other gastrointestinal peptides. Learn More

Human ETA Endothelin Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Human ETA Endothelin Receptor-expressing GPCR (G protein-coupled receptor) division-arrested cells. Endothelins are a family of vasoactive peptides including ET-1, ET-2 and ET-3 in human. The EDNRA receptors (ETA) have a much greater affinity for ET-1 over ET-3 and are expressed abundantly in vascular smooth muscles and stromal tissues. The vasoconstrictor and proliferative effects of ET-1 are primarily mediated by the EDNRA receptor. This makes EDNRA a good target for drug development in a number of cardiovascular diseases, including congestive heart failure, hypertension, stroke, kidney failure, and a variety of non-cardiovascular conditions, such as asthma, chronic obstructive pulmonary disease, pain and cancer. Learn More

Human H1 Histamine Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Human H1 Histamine Receptor-expressing GPCR (G protein-coupled receptor) division-arrested cells. Learn More

Human MrgX1 Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Human Mrg-X1 Receptor-expressing GPCR (G protein-coupled receptor) division-arrested cells. Learn More

Human MrgX2 Stable-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Human NTSR1 Neurotensin Receptor-expressing, stable replicating cell line. Learn More

Human P2Y11 Purinergic Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Human P2Y11 Purinergic Receptor-expressing GPCR (G protein-coupled receptor) division-arrested cells. Learn More

Human P2Y12 Purinergic Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Human P2Y6 Purinergic Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Human P2Y6 Purinergic Receptor-expressing GPCR (G protein-coupled receptor) division-arrested cells. Learn More

Human PAR2 Protease-Activated Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Human PAR2 Protease-Activated Receptor-expressing GPCR (G protein-coupled receptor) division-arrested cells. Learn More

Human PKR2 Prokineticin-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Human PKR2 Prokineticin Receptor-expressing GPCR (G protein-coupled receptor) division-arrested cells. Learn More