Frozen membranes from CHO-K1 cells expressing recombinant human CB2 Cannabinoid receptors. Learn More

Frozen membranes from CHO-K1 cells expressing recombinant rat CB2 Cannabinoid receptors. Learn More

Human Cholecystokinin CCKA Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Human CCKA Cholecystokinin Receptor-expressing GPCR (G protein-coupled receptor) division-arrested cells. Cholecystokinin (CCK) is a neuropeptide which is widely distributed in the mammalian central nervous system. The CCKA receptor has a limited distribution with highest densities in the hypothalamic nuclei, areas of the hippocampus, the septum, dorsal motor vagal nucleus and interpeduncular nucleus of the brain stem. It also occurs in numerous gastro-intestinal tissues. CCKA receptors affect satiety, pancreatitis, gut motility and have growth-promoting effects on some tumors. Learn More

Human Cholecystokinin CCKB Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Human CCKB Cholecystokinin Receptor-expressing GPCR (G protein-coupled receptor) division-arrested cells. Cholecystokinin (CCK) is a neuropeptide which is widely distributed in the mammalian central nervous system. The CCKB receptor is the predominant subtype in the CNS where it is widely distributed, however, it also occurs in abundance in the gastro-intestinal tract. CCKB receptors have been found to be most abundant in the cerebral cortex, cerebellum, basal ganglia, and amygdale. Animal and human studies using CCKB receptor antagonists have suggested that anxiety, panic attacks, analgesia, and satiety may be modulated through the CCKB receptor. Learn More

Human Chemokine CCR2B Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

non-recombinant Learn More

Frozen membranes from CHO-K1 cells Learn More

Human Delta Opioid Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Human Delta Opioid Receptor-expressing GPCR (G protein-coupled receptor) division-arrested cells. Learn More

Frozen membranes from CHO-K1 cells expressing recombinant human Edg1 receptors. Learn More

Human Edg-1 (S1P1) Lysophospholipid Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Frozen membranes from RH7777 cells expressing recombinant human EDG2 Lysophosphatidic Acid receptors. Learn More

Human ETA Endothelin Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Human ETA Endothelin Receptor-expressing GPCR (G protein-coupled receptor) division-arrested cells. Endothelins are a family of vasoactive peptides including ET-1, ET-2 and ET-3 in human. The EDNRA receptors (ETA) have a much greater affinity for ET-1 over ET-3 and are expressed abundantly in vascular smooth muscles and stromal tissues. The vasoconstrictor and proliferative effects of ET-1 are primarily mediated by the EDNRA receptor. This makes EDNRA a good target for drug development in a number of cardiovascular diseases, including congestive heart failure, hypertension, stroke, kidney failure, and a variety of non-cardiovascular conditions, such as asthma, chronic obstructive pulmonary disease, pain and cancer. Learn More

Human ETB Endothelin Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Human ETB Endothelin Receptor-expressing GPCR (G protein-coupled receptor) division-arrested cells. Endothelins are a family of vasoactive peptides that includes ET-1, ET-2 and ET-3. The EDNRA receptors have a much greater affinity for ET-1 over ET-3 and are expressed abundantly in vascular smooth muscles and stromal tissues. The EDNRB receptors bind ET-1, ET-2 and ET-3 with nearly equal affinity and are expressed abundantly in endothelial cells and epithelial tissues. Although the vasoconstrictor and proliferative effects of ET-1 are primarily mediated by EDNRA receptors, EDNRB receptors can also mediate the vasoconstrictor response through ET-1-induced nitric oxide release from endothelial cells. Learn More

Human FPRL1-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More