Human Serotonin 5HT2B Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Mouse 5HT2b Serotonin Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Human 5HT2B Serotonin Receptor-expressing GPCR (G protein-coupled receptor) division-arrested cells. Learn More

Mouse 5HT2B Serotonin Receptor-expressing GPCR (G protein-coupled receptor) division-arrested cells. Learn More

Frozen membranes from CHO-K1 cells expressing recombinant mouse 5HT2b Serotonin receptors. Learn More

Human Adenosine A1 Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Human A1 Adenosine Receptor-expressing GPCR (G protein-coupled receptor) division-arrested cells. Adenosine is a neuromodulator that is widely distributed in the central and peripheral nervous systems. Modulation of adenosine receptors by selective agonists and antagonists has potential for the treatment of various cardiovascular inflammatory and neurological diseases. Learn More

Human CFTR chloride ion channel-expressing, stable replicating cell line. Learn More

Human ETA Endothelin Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Human ETA Endothelin Receptor-expressing GPCR (G protein-coupled receptor) division-arrested cells. Endothelins are a family of vasoactive peptides including ET-1, ET-2 and ET-3 in human. The EDNRA receptors (ETA) have a much greater affinity for ET-1 over ET-3 and are expressed abundantly in vascular smooth muscles and stromal tissues. The vasoconstrictor and proliferative effects of ET-1 are primarily mediated by the EDNRA receptor. This makes EDNRA a good target for drug development in a number of cardiovascular diseases, including congestive heart failure, hypertension, stroke, kidney failure, and a variety of non-cardiovascular conditions, such as asthma, chronic obstructive pulmonary disease, pain and cancer. Learn More

Human ETB Endothelin Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. Learn More

Human ETB Endothelin Receptor-expressing GPCR (G protein-coupled receptor) division-arrested cells. Endothelins are a family of vasoactive peptides that includes ET-1, ET-2 and ET-3. The EDNRA receptors have a much greater affinity for ET-1 over ET-3 and are expressed abundantly in vascular smooth muscles and stromal tissues. The EDNRB receptors bind ET-1, ET-2 and ET-3 with nearly equal affinity and are expressed abundantly in endothelial cells and epithelial tissues. Although the vasoconstrictor and proliferative effects of ET-1 are primarily mediated by EDNRA receptors, EDNRB receptors can also mediate the vasoconstrictor response through ET-1-induced nitric oxide release from endothelial cells. Learn More

Human GABAA (α5/β2/γ2) ion channel-expressing, division-arrested cells. Learn More

Human GABAA (α5β2γ2) Receptor-expressing, stable replicating cell line. Learn More

Human KCa1.1 potassium ion channel-expressing, stable replicating cell line. Learn More

Human KCa1.1 potassium ion channel-expressing, division-arrested cells. Learn More

Human kCa3.1 potassium ion channel-expressing, stable replicating cell line. Learn More

Human KCa3.1 ion channel-expressing, division-arrested cells. Learn More

Human Kv1.3 potassium ion channel-expressing, stable replicating cell line (CHO). Learn More