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Background
The pituitary hormone vasopressin (AVP) is a cyclic nonapeptide that acts by binding to a family of vasopressin receptors that includes the V1a, V1b, and V2 receptors. V1b receptors are expressed in the anterior pituitary where they mediate ACTH release. Selective V1b antagonists have been shown to have anxiolytic and antidepressant effects.
| General Info | |
| Product Description | Frozen membranes from CHO-K1 cells expressing recombinant human V1b Vasopressin receptors. |
|---|---|
| Target Type | GPCR |
| Product Type | membrane |
| Receptor | Vasopressin |
| Sub-Type | V1b |
| Therapeutic Area | psychiatric disorder |
| Related Services | Membrane Preparation, GPCR Screening |
| Genbank Accession Number | NM_000707.2 |
| Membrane Info | |
| Host cell | CHO-K1 |
| Bmax | 7 pmol/mg protein |
| Recommended Assay Conditions | Refer to product specification sheet for details |
| Storage and Packaging | |
| Storage Recommendation | Storage at -80oC is recommended. Repeated freeze-thawing of this product is not recommended. |
| Media | |
| Specification Sheet |  Download PDF Document |
