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Background
Thromboxane A2 are prostanoids that cause contraction of vascular smooth muscle and aggregation of platelets. Two splice variants of the receptor for thromboxane A2 have been identified, that differ in their C-termini. This membrane preparation is derived from a cell line that expresses the beta splice variant found expressed primarily in endothelium.
| General Info | |
| Product Description | Frozen membranes from HEK293 cells expressing recombinant human Thromboxane receptors. |
|---|---|
| Target Type | GPCR |
| Product Type | membrane |
| Receptor | Thromboxane |
| Therapeutic Area | neurodegeneration & stroke, vascular |
| Related Services | Membrane Preparation, GPCR Screening |
| Genbank Accession Number | NM_001060 |
| Membrane Info | |
| Host cell | HEK293 |
| Bmax | 21 pmol/mg protein |
| KD | 14 nM |
| Recommended Assay Conditions | Refer to product specification sheet for details |
| Storage and Packaging | |
| Packaging | 0.4 mL of membrane suspension in storage buffer (10 mM HEPES in PBS, 0.38% sodium citrate, pH 7.4, 5 mM EDTA, 5 mM EGTA, 1 mM PMSF) at a protein concentration of 7 mg/mL |
| Storage Recommendation | 400 μl of membrane suspension in storage buffer (10 mM HEPES in PBS, 0.38% sodium citrate, pH 7.4, 5 mM EDTA, 5 mM EGTA, 1 mM PMSF) at a protein concentration of 7 mg/mL |
| Quantity | 400 µL/vial |
| Protein per vial | 2.8 mg |
| Media | |
| Specification Sheet |  Download PDF Document |
