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Background
GPR41 is a member of the free fatty acid G protein coupled receptor family and is activated by saturated and unsaturated carboxylic acids with carbon chain lengths equal to or less than six. Expression analysis shows that GPR41 is expressed in adipose tissue and to a lesser amount, in immune cells and elsewhere. GPR41 has been shown to be activated by short-chain fatty acids such as propionate.
| General Info | |
| Synonyms | FFAR3 |
|---|---|
| Product Description | Human GPR41 Receptor-expressing GPCR (G protein-coupled receptor) division-arrested cells. |
| Target Type | GPCR |
| Product Type | EZCells™ DA |
| Receptor | Free Fatty Acid |
| Sub-Type | GPR41 |
| Therapeutic Area | metabolic & gastrointestinal |
| Related Services | Membrane Preparation, GPCR Screening |
| Genbank Accession Number | NM_005304.2 and Ga16 |
| Validated Assay/Platform | calcium |
| References | Brown, A.J., et al., (2005) A Family of Fatty Acid Binding Receptors. DNA and Cell Biology 24: 54-61. Sawzdargo, M., et al (1997) A Cluster of four novel human G protein-coupled receptor genes occurring in close proximity to CD22 gene on chromo |
| EZCell Info | |
| Host cell | CHO-K1 |
| Mycoplasma Status | Negative (MycoAlert Kit) |
| Growth media | Ham's F12, 10% FBS, 1% NEAA, 400 µg/mL G418, 5 ?g/mL puromycin |
| Storage and Packaging | |
| Packaging | Cryopreserved irradiated cells, 6 million cells per vial |
| Storage Recommendation | liquid nitrogen |
| Quantity | 6 million cells |
| Media | |
| Specification Sheet |  Download PDF Document |
