Early Indication of Drug-Drug Interaction (DDI)
and hERG Risk
System: ChanTest’s FASTPatch automated patch clamp system (PatchXpress 7000A, QPatch) & Apredica’s P450 metabolic screening.
Benefits:
- Combined screen for hERG risk from DDI due to P450 substrate inhibition
| HERG-450TM Rapid Screen: |
| FASTPatch® Screen – Screen of hERG channel – (1 concentration @ n=2) |
| Rapid fluorescent Cyp3A4 inhibition screen – (1 concentration @ n=2) |
| HERG-450™ Profiling Screen: |
| Cardiac Channel PanelTM – Screen multiple cardiac ion channels |
| Fluorescent screen of Cyp3A4, plus 1A2, 2C9, 2C19, 2D6 |
Concentration-response curves or tabular results
hERG Risk Flyer