Key Personnel

ChanTest’s staff are experts in ion channels. Twenty percent are PhDs with years of experience measuring ion channel structure, function, correlations and pharmacology. Since its inception as an ion channel services company in 1998, ChanTest staff is dedicated to providing individual attention to serve each customer’s needs. Ion channel expertise includes molecular and cell biology, chemistry and biochemistry, electrophysiology, physiology, pharmacology, biophysics and clinical research.

Arthur M. “Buzz” Brown M.D., PhD., is founder and CEO. He is Adjunct Professor of Physiology and Biophysics, Case Western Reserve University School of Medicine. Previous academic positions were: Vice-President Research, CWRU and Chairman Department of Physiology and Biophysics Baylor College of Medicine. Dr. Brown has more than 30 years of experience in ion channel research. His laboratory was the first to: 1) identify the ion conduction pathways of voltage-gated and inwardly rectifying potassium channels using a combination of mutagenesis and patch clamp; 2) show that hERG was the molecular target for non-antiarrhythmic, torsadogenic drugs; and 3) show that drugs may be torsadogens by inhibiting hERG trafficking. He holds numerous patents on ion channels and treatment of cardiac arrhythmias.