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Early Indication of Drug-Drug Interaction (DDI) and hERG Risk
System: ChanTest’s FASTPatch automated patch clamp system (PatchXpress 7000A, QPatch) & Apredica’s P450 metabolic screening
Benefits:
- Combined screen for hERG risk from DDI due to P450 substrate inhibition
Available screens:
| HERG-450TM Rapid Screen: |
- FASTPatch® Screen – Screen of hERG channel – (1 concentration @ n=2)
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- Rapid fluorescent Cyp3A4 inhibition screen – (1 concentration @ n=2)
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| HERG-450™ Profiling Screen: |
- Cardiac Channel PanelTM – Screen multiple cardiac ion channels
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- Fluorescent screen of Cyp3A4, plus 1A2, 2C9, 2C19, 2D6
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Concentration-response curves or tabular results
 SAB-hERG 450.pdf
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